Matériaux et Phénomènes Quantiques
Présentation
The laboratory « Matériaux et Phénomènes Quantiques » (Quantum Materials and Phenomena) is a joint research unit (UMR) of University Paris Diderot and CNRS. It involves about 120 people in total with a permanent staff of 51.
The laboratory specializes in the study of frontier quantum materials and in the development of novel quantum devices. These activities rely on a large spectrum of theoretical and experimental expertise in material physics, transport and optics, and technological platforms of clean-room fabrication, spectroscopy and high-resolution electronic microscopy.
The activities of the laboratory span:
- novel materials at the nanoscale: nanocrystals, functionalized nanotubes, multiferroics, 2D materials, etc.
- novel phases of matter: quantum fluids of light, ultrastrong coupling in cavity, unconventional superconductivity, strongly correlated systems, topological phases, etc.
- nano-optical systems: optomechanics, nonlinear nanophotonics, nanoplasmonics, etc.
- quantum engineering and quantum information: quantum optoelectronic devices, quantum photonic circuits, trapped ions, hybrid organic/inorganic devices, surface and interface engineering.
Current projects of the laboratory include the development of novel probes for the investigation of quantum materials, such as time-resolved Raman spectroscopy, optomechanical atomic force microscopy, and scanning tunneling microscopy under optical excitation. Reciprocally, frontier materials are being tested as building blocks to realize novel functionalities in optomechanical sensors, nonlinear and quantum photonics devices, or in cavity embedded transport experiments.
[cea-04717059] Corrosion products formed on MgZr Alloy embedded in Geopolymer used as conditioning matrix for nuclear waste-Aproposition of interconnected processes
Date: 1 Oct 2024 - 17:22
Desc: [...]
[hal-01470388] Intracellular degradation of functionalized carbon nanotube/iron oxide hybrids is modulated by iron via Nrf2 pathway
Date: 17 Feb 2017 - 13:22
Desc: The in vivo fate and biodegradability of carbon nanotubes is still a matter of debate despite tremendous applications. In this paper we describe a molecular pathway by which macrophages degrade functionalized multi-walled carbon nanotubes (CNTs) designed for biomedical applications and containing, or not, iron oxide nanoparticles in their inner cavity. Electron microscopy and Raman spectroscopy show that intracellularly-induced structural damages appear more rapidly for iron-free CNTs in comparison to iron-loaded ones, suggesting a role of iron in the degradation mechanism. By comparing the molecular responses of macrophages derived from THP1 monocytes to both types of CNTs, we highlight a molecular mechanism regulated by Nrf2/Bach1 signaling pathways to induce CNT degradation via NOX 2 complex activation and O 2 • − , H 2 O 2 and OH • production. CNT exposure activates an oxidative stress-dependent production of iron via Nrf2 nuclear translocation, Ferritin H and Heme oxygenase 1 translation. Conversely, Bach1 was translocated to the nucleus of cells exposed to iron-loaded CNTs to recycle embedded iron. Our results provide new information on the role of oxidative stress, iron metabolism and Nrf2-mediated host defence for regulating CNT fate in macrophages.
[hal-02465950] Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers
Date: 4 Feb 2020 - 11:14
Desc: Allergic contact dermatitis (ACD) represents a severe health problem with increasing worldwide prevalence. It is a T-cell-mediated inflammatory skin disease caused by chemicals present in the daily or professional environment. NiSO4 and 2,4-dinitrochlorobenzene (DNCB) are 2 chemicals involved in ACD. These contact sensitizers are known to induce an up-regulation of phenotypic markers and cytokine secretion in dendritic cells (DCs; professional APCs), leading to the generation of CD8+ Tc1/Tc17 and CD4+ Th1/Th17 effector T cells. In the present study, using a peptide array approach, we identified protein kinase CK2 as a novel kinase involved in the activation of human monocyte-derived DCs (MoDCs) in response to NiSO4 and DNCB. Inhibition of CK2 activity in MoDCs led to an altered mature phenotype with lower expression of CD54, PDL-1, CD86, and CD40 in response to NiSO4 or DNCB. CK2 activity also regulated proinflammatory cytokine production, such as TNF-α, IL-1β, and IL-23 in MoDCs. Moreover, in a DC/T cell coculture model in an allogeneic setup, CK2 activity in MoDCs played a major role in Th1 polarization in response to NiSO4 and DNCB. CK2 inhibition in MoDCs led to an enhanced Th2 polarization in the absence of contact sensitizer stimulation.
[hal-02525158] Utilisation de fibres à couplage inhibé pour le controle de l'intrication spectrale de paires de photons
Date: 30 Mar 2020 - 18:56
Desc: [...]
Autres contacts
Université Paris Diderot - Paris 7
U.F.R. Physique
Bâtiment Condorcet
10, rue Alice Domon et Léonie Duquet
75205 PARIS CEDEX 13